文章来源:www.cnzx.com.cn 作者: 发表日期:2008-3-10 19:32:42 |
中国海洋大学教授梁世德
梁世德,男,1971年10生。留美博士后,现为中国海洋大学副教授。已发表论文10篇。其中Sci索引9篇。在实验生物学和物理化学理论方面受过严格训练。基础知识扎实,对数学、物理、化学、生物学,和计算机算法都有较深的了解。攻读博士期间,在国际上首次提出算法,把蛋白-蛋白相互作用区嫁接到非同源的骨架蛋白上。2002年完成的蛋白质侧链构象预测程序,在国际上至今仍保持最高的预测精度。目前主要从事文昌鱼生物信息学和蛋白质计算生物学的研究。
近年来发表的主要论文:
1. Shide Liang,Jian Zhang, Shicui Zhang, and Huarong Guo Prediction of the Interaction Site on the Surface of an Isolated Protein Structure by Analysis of Side Chain Energy Scores Proteins (in press) 2. Shide Liang and Nick V. Grishin Effectvie scoring funcion for protein sequence design 2004 Proteins 54:271-281 3. Liu Zhijie, Jiang Lin, Gao Ying, Liang Shide, Chen Hao, Han Yuzhen and Lai Luhua, Beyond the rotamer library: genetic algorithm combined with the disturbing mutation process for upbuilding protein side-chains.2003 Proteins 50:49-62 4. Shide Liang and Nick V. Grishin Side-chain modeling with an optimized scoring function. Protein Science 2002 11: 322-33 5. Shide Liang, Zhijie Liu, and Luhua Lai, Construction of protein binding site on known structure. Biopolymers 2000 54:515-523 6. Shide Liang, Weizhong Li, Lan Xiao, Jiansuo Wang, and Luhua Lai, Grafting of Protein-Protein interaction epiope. Journal of Biomolecular Structure & Dynamics 2000 17:821-838 7. LIANG Shide,XIAO Lan,MAO Fenglou,JIANG Lin, Han Yuzhen, and LAI Luhua, Grafting of protein binding site. Chinese Science Bulletin(中国科学通报英语版) 2000 45:1707-1711 8. Weizhong Li, Shide Liang, Renxiao Wang, Luhua Lai, and Yuzhen Han, Exploring the conformational diversity of loops on conserved frameworks. Protein Engineering 1999 12: 1075-1086 9.LI Weizhong,LIU Zhijie,LIANG Shide,HAN Yuzhen and LAI Luhua,Rational screen in combinatorial peptide libraries of protein functional loop. Chinese science Bulletin(中国科学通报英语版) 1999 44:2150-2154
相关内容
下列内容与中国海洋大学 蛋白质侧链构象预测程序有着内在的联系,建议您一并阅读。
